Diagnosis of viral and chlamydial keratoconjunctivitis: which laboratory test?

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Diagnosis of viral and chlamydial keratoconjunctivitis: which laboratory test?

Conjunctivitis and keratitis are common forms of ocular morbidity seen in general practice and eye units. 2 The aetiology of these diseases includes viral, bacterial, or parasitic infection as well as allergy, trauma, and dietary deficiency. Among the common microbial causes (Table 1) are adenovirus, herpes simplex virus (HSV), and Chlamydia trachomatis. Ocular adenovirus infections occur throu...

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Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis.

PURPOSE To develop a multiplex polymerase chain reaction (PCR) for the detection of adenovirus, herpes simplex virus, and Chlamydia trachomatis in conjunctival swabs. METHODS Oligonucleotide primers for detection of the 3 agents were combined in one reaction and evaluated for optimal performance using control DNAs of adenovirus type 2, herpes simplex virus, and C. trachomatis plasmid. The mul...

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Laboratory diagnosis of persistent human chlamydial infection

Diagnostic assays for persistent chlamydial infection are much needed to conduct high-quality, large-scale studies investigating the persistent state in vivo, its disease associations and the response to therapy. Yet in most studies the distinction between acute and persistent infection is based on the interpretation of the data obtained by the assays developed to diagnose acute infections or o...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1999

ISSN: 0007-1161

DOI: 10.1136/bjo.83.5.622